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Olodaterol hydrochloride

CAS No. 869477-96-3

Olodaterol hydrochloride ( BI1744 CL )

Catalog No. M16316 CAS No. 869477-96-3

Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Olodaterol hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2.
  • Description
    Olodaterol hydrochloride (BI1744 CL) is a potent, selective long-acting β2 adrenoceptor agonist with EC50 of 1.4 nM for hβ2; shows >250 fold selectivity over hβ1; exerts a bronchodilatory efficacy over 24 h in dogs and guinea pigs in the absence of systemic pharmacodynamic effects.COPD Phase 3 Clinical
  • Synonyms
    BI1744 CL
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    hβ2-adrenoceptor
  • Research Area
    Inflammation/Immunology
  • Indication
    COPD

Chemical Information

  • CAS Number
    869477-96-3
  • Formula Weight
    413.90
  • Molecular Formula
    C21H17ClFN3OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 50 mg/mL; Water: 15 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    CC(C)(CC1=CC=C(C=C1)OC)NCC(C2=C3C(=CC(=C2)O)NC(=O)CO3)O.Cl
  • Chemical Name
    4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine hydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bouyssou T, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1410-4.
2. Bouyssou T, et al. J Pharmacol Exp Ther. 2010 Jul;334(1):53-62.
3. Wex E, et al. Br J Pharmacol. 2015 Jul;172(14):3537-47.
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